Significance of Plasma UCA1 for Predicting Colorectal Cancer and BRAF Mutation Status
نویسندگان
چکیده
Background: Clinical significance of plasma urothelial carcinoma associated 1 (UCA1) in patients with colorectal cancer (CRC) remains unclear. This study investigated the usefulness UCA1 as a biomarker CRC. Materials and Methods: levels were measured tissue from CRC by quantitative polymerase chain reaction. Relationships between clinicopathological features examined. Results: Plasma significantly lower than healthy volunteers. expression B-Raf proto-oncogene serine/threonine kinase (BRAF)-mutant was also that non-cancerous tissue, although it higher wild-type BRAF. In right-sided CRC, level pT4 BRAF mutation. contrast, left-sided pStage 3b-4. Conclusion: is useful for detection predicting features, particularly
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ژورنال
عنوان ژورنال: Anticancer Research
سال: 2021
ISSN: ['0250-7005', '1791-7530']
DOI: https://doi.org/10.21873/anticanres.14941